书目详细信息
： Molecular basis of drug action :
书目信息 机读格式(MARC)
| ISBN： | 044400632X |
|---|---|
| 编目源： | DLC DLC DLC |
| 中图分类： | R963-53 |
| 会议名称： | International Symposium on Molecular Basis of Drug Action |
| 题名： | Molecular basis of drug action : proceedings of the International Symposium on Molecular Basis of Drug Action, held in Querétaro, Mexico, October 13-16, 1980 / editors, Thomas P. Singer, Raúl N. Ondarza. |
| 出版发行项： | New York, N.Y. : Elsevier/North-Holland, c1981. |
| 载体形态： | xix, 408 p. : ill. ; 25 cm. |
| 丛编说明： | Developments in biochemistry, 016-1714 ; v. 19 |
| 书目附注： | Includes bibliographies and index. |
| 格式化内容附注： | Drugs against microbial invaders: Mode of action penicillins and ³-cephalosporins: on the active centers of serine and Zn₊₊ D-alanyl-D-Ala peptidase / J.M. Ghuysen, J.-M. Frere, and M. Leyh-Bouille. Modern science and the design of drugs for infectious disease / S.S. Cohen. Biochemical and molecular strategies in chemotherapy of parasitic worm infections / T.E. Mansour. Mutasynthesis of antibiotics / K.L. Rinehart, Jr. -- Suicide inhibitors, the search for perfect drugs: Introduction / Usdin. Overview / T.P. Singer. Suicide inhibitors of GABA transaminase / B.W. Metcalf and A. Sjoerdsma. Enzyme-activated irreversible inhibitors of [alpha]-amino acid decarboxylases / M.J. Jung and J. Koch-Weser. Olefins as suicide inhibitors of cytochrome P-450 / P.R. Ortiz de Montellano, B.A. Mico, H.S. Beilan, and K.L. Kunze. Mechanism-based inactivators of pyridoxal phosphate enzymes / M. Johnston and C. Walsh. Can the suicide inactivation of MAO by deprenyl explain its pharmacological effects? / J. Knoll -- New directions in molecular pharmacology: Drug transport / D. Zakim. The design of thyroid drugs / E.C. Jorgensen. Angiotensin-converting enzyme inhibition: further explorations of an active-site model / M.A. Ondetti ... [et al.]. A serontoninergic antihypertensive agent / E. Hong. Investigation of electrostatic structure of membranes: new approaches with spin labelling / David S. Cafiso, W. Hubbell. The dual action of opioids and opioid-specific neuronal kindling / J.E. Villarreal -- Ionic channels and pumps: New perspectives on the tetrodotoxin and saxitoxin receptors / C.Y. Kao. The sodium and potassium ion pump / R.L. Post. Structure and function of the voltage-dependent sodium channel / S.R. Levinson -- Mechanisms of drug resistance: Penam sulfone inhibition of the RTEM [beta]-lactamase / D.G. Brenner, J. Fisher, and C. Kemal. Gene amplification as a mechanism for drug resistance in cultured animal cells / C.C. Simonsen ... [et al.]. The induction of cytochromes P-450 related to drug, steroid, and carcinogen metabolism / R.W. Estabrook ... [et al.]. Aspects of enzyme-mediated aminoglycoside antibiotic resistance / M.J. Haas and J. Davies |